Drug reference
montelukast
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Respiratory (Leukotrienes Antagonist)
Mechanism of action
Blocks binding of leukotriene D4 to its receptor; alters pathophysiology associated with inflammatory process that contributes to signs and symptoms of asthma.
Common side effects
- Headache
- Eczema
- Abdominal pain
Boxed warnings
- FDA announcement March 4, 2020 Serious neuropsychiatric events that may include suicidal thoughts or actions have been reported in patients taking montelukast Only use montelukast for allergic rhinitis in patients who have an inadequate response or intolerance to alternative therapies Consider risks and benefits when prescribing or continuing treatment Advise all patients of the risk of neuropsychiatric events when prescribing Discontinue and contact a health care professional immediately if changes in behavior or new neuropsychiatric symptoms, suicidal thoughts, or behavior oc…
Contraindications
- Hypersensitivity
Related conditions
Frequently asked questions
What drug class is montelukast?
montelukast belongs to: Respiratory.
How does montelukast work?
Blocks binding of leukotriene D4 to its receptor; alters pathophysiology associated with inflammatory process that contributes to signs and symptoms of asthma.
What are the common side effects of montelukast?
Headache, Eczema, Abdominal pain
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