Drug interactions
Amiloride + Maraviroc
Severity: Minor
Amiloride and Maraviroc: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, particularly in patients with renal impairment or on blood pressure lowering drugs. Amiloride may add to this through volume depletion.
What this interaction means in plain words
Amiloride and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiloride belongs to Cardiovascular; Maraviroc belongs to Anti Virals.
Why it happens
Additive hypotensive effects; the mechanism is pharmacodynamic.
What to do
Monitor for orthostatic symptoms and blood pressure, especially in patients with renal impairment. Adjust the diuretic dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amiloride
- Amiloride + Eplerenone Contraindicated
- Amiloride + Spironolactone Contraindicated
- Amiloride + Triamterene Contraindicated
- Aceclofenac + Amiloride Major
- Acemetacin + Amiloride Major
- Amiloride + Amlodipine-benazepril Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Amiloride with Maraviroc?
MediHelp rates the interaction as minor. Amiloride and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc can cause postural hypotension, particularly in patients with renal impairment or on blood pressure lowering drugs. Amiloride may add to this through volume depletion.
How serious is the interaction between Amiloride and Maraviroc?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for orthostatic symptoms and blood pressure, especially in patients with renal impairment. Adjust the diuretic dose if needed.
What other medicines interact with Amiloride?
MediHelp also lists interactions of Amiloride with, for example, Eplerenone, Spironolactone, Triamterene. The full list is on the Amiloride page.
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