Drug interactions
amiodarone + ondansetron
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Additive QT prolongation → torsades risk.
Mechanism of action
IKr blockade synergy.
Clinical management
Avoid or monitor ECG/electrolytes.
Drug reference
References
Frequently asked questions
Can I take amiodarone with ondansetron?
The interaction is rated: Major. Additive QT prolongation → torsades risk.
How serious is the interaction between amiodarone and ondansetron?
The interaction is rated: Major. Evidence level: Moderate.
How is the interaction between amiodarone and ondansetron managed?
Avoid or monitor ECG/electrolytes.
Why do amiodarone and ondansetron interact?
IKr blockade synergy.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.