Drug interactions
Amisulpride + Arformoterol
Severity: Moderate
Amisulpride and Arformoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amisulpride prolongs the QT interval in a dose-related way, and high-dose beta-agonists such as arformoterol can also prolong QTc and cause hypokalemia. Together the risk of torsades de pointes may rise.
What this interaction means in plain words
Amisulpride and Arformoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amisulpride belongs to Central Nervous System; Arformoterol belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia as a further contributor.
What to do
Obtain a baseline ECG and monitor QTc and serum potassium. Correct electrolyte disturbances and use the lowest effective doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amisulpride
- Amiodarone + Amisulpride Contraindicated
- Amisulpride + Arsenic trioxide Contraindicated
- Amisulpride + Disopyramide Contraindicated
- Amisulpride + Dofetilide Contraindicated
- Amisulpride + Droperidol Contraindicated
- Amisulpride + Ibutilide Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Amisulpride with Arformoterol?
MediHelp rates the interaction as moderate. Amisulpride and Arformoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amisulpride prolongs the QT interval in a dose-related way, and high-dose beta-agonists such as arformoterol can also prolong QTc and cause hypokalemia. Together the risk of torsades de pointes may rise.
How serious is the interaction between Amisulpride and Arformoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor QTc and serum potassium. Correct electrolyte disturbances and use the lowest effective doses.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
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