Drug reference
amisulpride
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic (atypical))
Mechanism of action
Selective dopamine-2 (D2) and dopamine-3 (D3) receptor antagonist, D2 receptors are located in the chemoreceptor trigger zone (CTZ) and respond to the dopamine released from the nerve endings, Activation of CTZ relays stimuli to the vomiting center, which is involved in emesis
Common side effects
- Increased blood prolactin
- Procedural hypotension
- Abdominal distension
Known interactions (22)
- amisulpride + pimozide Contraindicated
- amisulpride + pramipexole Contraindicated
- amisulpride + ropinirole Contraindicated
- amisulpride + thioridazine Contraindicated
- amisulpride + aripiprazole Major
- amisulpride + asenapine Major
- amisulpride + brexpiprazole Major
- amisulpride + cariprazine Major
- amisulpride + chlorpromazine Major
- amisulpride + clozapine Major
- amisulpride + dronedarone Major
- amisulpride + fluphenazine Major
- amisulpride + haloperidol Major
- amisulpride + loxapine Major
- amisulpride + lurasidone Major
- amisulpride + olanzapine Major
- amisulpride + paliperidone Major
- amisulpride + perphenazine Major
- amisulpride + prochlorperazine Major
- amisulpride + quetiapine Major
- amisulpride + risperidone Major
- amisulpride + ziprasidone Major
Related conditions
Frequently asked questions
What drug class is amisulpride?
amisulpride belongs to: Central Nervous System.
How does amisulpride work?
Selective dopamine-2 (D2) and dopamine-3 (D3) receptor antagonist, D2 receptors are located in the chemoreceptor trigger zone (CTZ) and respond to the dopamine released from the nerve endings, Activation of CTZ relays stimuli to the vomiting center, which is involved in emesis
What are the common side effects of amisulpride?
Increased blood prolactin, Procedural hypotension, Abdominal distension
Which drugs interact with amisulpride?
pimozide, pramipexole, ropinirole, thioridazine, aripiprazole, asenapine, brexpiprazole, cariprazine, chlorpromazine, clozapine, dronedarone, fluphenazine, haloperidol, loxapine, lurasidone
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.