Drug interactions
Amisulpride + Indacaterol inhaled
Severity: Moderate
Amisulpride and Indacaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta-2 agonists such as indacaterol can cause hypokalemia and minor QT changes. With amisulpride, the QT-prolonging effect may be increased, though the risk at recommended doses is small.
What this interaction means in plain words
Amisulpride and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT effects, with beta-agonist induced hypokalemia contributing to arrhythmia risk.
What to do
Use recommended indacaterol doses and monitor serum potassium in at-risk patients. Obtain an ECG if other QT risk factors are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amisulpride
- Amiodarone + Amisulpride Contraindicated
- Amisulpride + Arsenic trioxide Contraindicated
- Amisulpride + Disopyramide Contraindicated
- Amisulpride + Dofetilide Contraindicated
- Amisulpride + Droperidol Contraindicated
- Amisulpride + Ibutilide Contraindicated
Frequently asked questions
Can I take Amisulpride with Indacaterol inhaled?
MediHelp rates the interaction as moderate. Amisulpride and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Beta-2 agonists such as indacaterol can cause hypokalemia and minor QT changes. With amisulpride, the QT-prolonging effect may be increased, though the risk at recommended doses is small.
How serious is the interaction between Amisulpride and Indacaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use recommended indacaterol doses and monitor serum potassium in at-risk patients. Obtain an ECG if other QT risk factors are present.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
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