Drug interactions
Amlodipine-atorvastatin + Terazosin
Severity: Moderate
Amlodipine-atorvastatin and Terazosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both amlodipine and terazosin lower blood pressure through vasodilation. Together they can cause excessive hypotension, dizziness and syncope, particularly after the first dose or a dose increase.
What this interaction means in plain words
Amlodipine-atorvastatin and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-atorvastatin belongs to Cardiovascular; Terazosin belongs to Genitourinary.
Why it happens
Additive vasodilation through calcium channel blockade and alpha-1 adrenergic receptor blockade.
What to do
Monitor blood pressure, including standing readings, when starting or adjusting either drug. Give the first terazosin dose at bedtime and titrate slowly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-atorvastatin
Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Frequently asked questions
Can I take Amlodipine-atorvastatin with Terazosin?
MediHelp rates the interaction as moderate. Amlodipine-atorvastatin and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both amlodipine and terazosin lower blood pressure through vasodilation. Together they can cause excessive hypotension, dizziness and syncope, particularly after the first dose or a dose increase.
How serious is the interaction between Amlodipine-atorvastatin and Terazosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, including standing readings, when starting or adjusting either drug. Give the first terazosin dose at bedtime and titrate slowly.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
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