Drug interactions
Amlodipine-benazepril + Arsenic trioxide
Severity: Minor
Amlodipine-benazepril and Arsenic trioxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arsenic trioxide can cause QT prolongation, electrolyte disturbances and fluid shifts, and may cause hypotension. Antihypertensives add little direct risk, but hypotension and volume depletion can complicate electrolyte management in patients receiving arsenic trioxide.
What this interaction means in plain words
Amlodipine-benazepril and Arsenic trioxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Arsenic trioxide belongs to Oncology.
Why it happens
Possible additive hypotension; no direct pharmacokinetic interaction is established.
What to do
Monitor blood pressure, potassium, magnesium and ECG per arsenic trioxide protocol and hold antihypertensives if hypotension or volume depletion develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Arsenic trioxide
- Amiodarone + Arsenic trioxide Contraindicated
- Amisulpride + Arsenic trioxide Contraindicated
- Arsenic trioxide + Clomipramine Contraindicated
- Arsenic trioxide + Dronedarone Contraindicated
- Arsenic trioxide + Fluphenazine Contraindicated
- Arsenic trioxide + Gemifloxacin Contraindicated
Frequently asked questions
Can I take Amlodipine-benazepril with Arsenic trioxide?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Arsenic trioxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Arsenic trioxide can cause QT prolongation, electrolyte disturbances and fluid shifts, and may cause hypotension. Antihypertensives add little direct risk, but hypotension and volume depletion can complicate electrolyte management in patients receiving arsenic trioxide.
How serious is the interaction between Amlodipine-benazepril and Arsenic trioxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, potassium, magnesium and ECG per arsenic trioxide protocol and hold antihypertensives if hypotension or volume depletion develops.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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