Drug interactions
Amlodipine-olmesartan-hydrochlorothiazide + Ampicillin
Severity: Minor
Amlodipine-olmesartan-hydrochlorothiazide and Ampicillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide may modestly reduce renal clearance of ampicillin and raise its levels. This is generally of little clinical significance.
What this interaction means in plain words
Amlodipine-olmesartan-hydrochlorothiazide and Ampicillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Ampicillin belongs to Anti Bacterial.
Why it happens
Competition for renal tubular secretion of organic anions, plus possible volume-related reduction in clearance.
What to do
No action is usually needed; consider monitoring renal function in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Major
Other interactions of Ampicillin
- Allopurinol + Ampicillin Moderate
- Ampicillin + Bcg vaccine live Moderate
- Ampicillin + Chloramphenicol Moderate
- Ampicillin + Chloroquine Moderate
- Ampicillin + Cholera vaccine Moderate
- Ampicillin + Demeclocycline Moderate
Frequently asked questions
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Ampicillin?
MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Ampicillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide may modestly reduce renal clearance of ampicillin and raise its levels. This is generally of little clinical significance.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Ampicillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is usually needed; consider monitoring renal function in patients with renal impairment.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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