Drug interactions
Amlodipine-olmesartan-hydrochlorothiazide + Calcium acetate
Severity: Minor
Amlodipine-olmesartan-hydrochlorothiazide and Calcium acetate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium salts can theoretically reduce the effect of calcium channel blockers, but oral calcium at ordinary doses rarely changes amlodipine efficacy. Thiazide combined with calcium can raise serum calcium, which is more relevant clinically.
What this interaction means in plain words
Amlodipine-olmesartan-hydrochlorothiazide and Calcium acetate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Calcium acetate belongs to Genitourinary.
Why it happens
Raised extracellular calcium may theoretically antagonize calcium channel blockade; thiazide reduces urinary calcium excretion.
What to do
Monitor serum calcium in patients on thiazides taking calcium supplements or binders, and check blood pressure if control seems reduced.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Major
Other interactions of Calcium acetate
Frequently asked questions
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Calcium acetate?
MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Calcium acetate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium salts can theoretically reduce the effect of calcium channel blockers, but oral calcium at ordinary doses rarely changes amlodipine efficacy. Thiazide combined with calcium can raise serum calcium, which is more relevant clinically.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Calcium acetate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium in patients on thiazides taking calcium supplements or binders, and check blood pressure if control seems reduced.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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