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Drug interactions

Amlodipine-perindopril + Betaxolol

Severity: Minor

Amlodipine-perindopril and Betaxolol: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Betaxolol adds to the blood pressure lowering of amlodipine and perindopril, which is often useful. Hypotension or bradycardia can occur in some patients.

What this interaction means in plain words

Amlodipine-perindopril and Betaxolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-perindopril belongs to Cardiovascular; Betaxolol belongs to Cardiovascular.

Evidence level: High

Why it happens

Additive antihypertensive effects from beta-blockade, calcium channel blockade and ACE inhibition.

What to do

Monitor blood pressure and heart rate when initiating or titrating.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-perindopril with Betaxolol?

MediHelp rates the interaction as minor. Amlodipine-perindopril and Betaxolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Betaxolol adds to the blood pressure lowering of amlodipine and perindopril, which is often useful. Hypotension or bradycardia can occur in some patients.

How serious is the interaction between Amlodipine-perindopril and Betaxolol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when initiating or titrating.

What other medicines interact with Amlodipine-perindopril?

MediHelp also lists interactions of Amlodipine-perindopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Amlodipine-perindopril page.

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