Drug interactions
Amlodipine-perindopril + Insulin inhaled
Severity: Moderate
Amlodipine-perindopril and Insulin inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors can enhance insulin sensitivity, increasing the hypoglycemic effect of insulin. Hypoglycemia risk is greatest soon after starting the ACE inhibitor.
What this interaction means in plain words
Amlodipine-perindopril and Insulin inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Improved insulin sensitivity with ACE inhibition adds to insulin's glucose-lowering effect.
What to do
Monitor blood glucose more closely when perindopril is started or adjusted. Reduce insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-perindopril
- Aliskiren + Amlodipine-perindopril Contraindicated
- Amlodipine-perindopril + Protein a column Contraindicated
- Amlodipine-perindopril + Sacubitril / valsartan Contraindicated
- Amifostine + Amlodipine-perindopril Major
- Amiloride + Amlodipine-perindopril Major
- Amlodipine-perindopril + Azilsartan Major
Frequently asked questions
Can I take Amlodipine-perindopril with Insulin inhaled?
MediHelp rates the interaction as moderate. Amlodipine-perindopril and Insulin inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. ACE inhibitors can enhance insulin sensitivity, increasing the hypoglycemic effect of insulin. Hypoglycemia risk is greatest soon after starting the ACE inhibitor.
How serious is the interaction between Amlodipine-perindopril and Insulin inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more closely when perindopril is started or adjusted. Reduce insulin dose if hypoglycemia occurs.
What other medicines interact with Amlodipine-perindopril?
MediHelp also lists interactions of Amlodipine-perindopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Amlodipine-perindopril page.
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