Drug interactions
Amlodipine-valsartan + Armodafinil
Severity: Minor
Amlodipine-valsartan and Armodafinil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil is a weak CYP3A4 inducer and may slightly lower amlodipine concentrations. Armodafinil can also raise blood pressure, which may offset antihypertensive therapy.
What this interaction means in plain words
Amlodipine-valsartan and Armodafinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-valsartan belongs to Cardiovascular; Armodafinil belongs to Central Nervous System.
Why it happens
Weak induction of CYP3A4 increases amlodipine clearance.
What to do
Monitor blood pressure after starting or stopping armodafinil and adjust the amlodipine dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-valsartan
- Aliskiren + Amlodipine-valsartan Contraindicated
- Amlodipine-valsartan + Sparsentan Contraindicated
- Aldesleukin + Amlodipine-valsartan Major
- Amifostine + Amlodipine-valsartan Major
- Amiloride + Amlodipine-valsartan Major
- Amlodipine-valsartan + Benazepril Major
Other interactions of Armodafinil
Frequently asked questions
Can I take Amlodipine-valsartan with Armodafinil?
MediHelp rates the interaction as minor. Amlodipine-valsartan and Armodafinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil is a weak CYP3A4 inducer and may slightly lower amlodipine concentrations. Armodafinil can also raise blood pressure, which may offset antihypertensive therapy.
How serious is the interaction between Amlodipine-valsartan and Armodafinil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure after starting or stopping armodafinil and adjust the amlodipine dose if needed.
What other medicines interact with Amlodipine-valsartan?
MediHelp also lists interactions of Amlodipine-valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Amlodipine-valsartan page.
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