Drug interactions
Amphotericin b liposomal + Captopril
Severity: Minor
Amphotericin b liposomal and Captopril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Liposomal amphotericin B does not have a meaningful direct blood pressure lowering effect, though infusion reactions can cause hypotension. It may cause nephrotoxicity and electrolyte disturbance, which are relevant in patients taking an ACE inhibitor.
What this interaction means in plain words
Amphotericin b liposomal and Captopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amphotericin b liposomal belongs to Anti Fungals; Captopril belongs to Cardiovascular.
Why it happens
No direct pharmacodynamic synergy established; amphotericin nephrotoxicity may add to ACE inhibitor renal effects.
What to do
Monitor renal function and potassium during amphotericin therapy. Review captopril if renal function declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril
- Aliskiren + Captopril Contraindicated
- Captopril + Sacubitril / valsartan Contraindicated
- Captopril + Sacubitril-valsartan Contraindicated
- Amifostine + Captopril Major
- Amiloride + Captopril Major
- Amlodipine-hydrochlorothiazide-valsartan + Captopril Major
Other interactions of Amphotericin b liposomal
- Amlodipine-benazepril + Amphotericin b liposomal Moderate
- Amphotericin b liposomal + Benazepril Moderate
- Amphotericin b liposomal + Captopril-hydrochlorothiazide Moderate
- Amphotericin b liposomal + Deflazacort Moderate
- Amphotericin b liposomal + Dichlorphenamide Moderate
- Amphotericin b liposomal + Ifosfamide Moderate
Frequently asked questions
Can I take Amphotericin b liposomal with Captopril?
MediHelp rates the interaction as minor. Amphotericin b liposomal and Captopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Liposomal amphotericin B does not have a meaningful direct blood pressure lowering effect, though infusion reactions can cause hypotension. It may cause nephrotoxicity and electrolyte disturbance, which are relevant in patients taking an ACE inhibitor.
How serious is the interaction between Amphotericin b liposomal and Captopril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and potassium during amphotericin therapy. Review captopril if renal function declines.
What other medicines interact with Captopril?
MediHelp also lists interactions of Captopril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Captopril page.
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