Drug interactions
Anastrozole + Mirtazapine
Severity: Minor
Anastrozole and Mirtazapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anastrozole is a weak inhibitor of some CYP enzymes in vitro and is not known to meaningfully affect mirtazapine exposure. No clinically significant interaction has been established.
What this interaction means in plain words
Anastrozole and Mirtazapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Anastrozole belongs to Oncology; Mirtazapine belongs to Central Nervous System.
Why it happens
Theoretical weak CYP3A4 inhibition; clinical relevance not established.
What to do
No specific action needed beyond routine monitoring of mirtazapine tolerability.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mirtazapine
- Isocarboxazid + Mirtazapine Contraindicated
- Mirtazapine + Phenelzine Contraindicated
- Mirtazapine + Pimozide Contraindicated
- Mirtazapine + Procarbazine Contraindicated
- Mirtazapine + Rasagiline Contraindicated
- Mirtazapine + Selegiline Contraindicated
Other interactions of Anastrozole
- Anastrozole + Bazedoxifene / conjugated estrogens Contraindicated
- Anastrozole + Bazedoxifene-conjugated estrogens Contraindicated
- Anastrozole + Conjugated estrogens Contraindicated
- Anastrozole + Estradiol Contraindicated
- Anastrozole + Estrogens conjugated synthetic Contraindicated
- Anastrozole + Estrogens esterified Contraindicated
Frequently asked questions
Can I take Anastrozole with Mirtazapine?
MediHelp rates the interaction as minor. Anastrozole and Mirtazapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Anastrozole is a weak inhibitor of some CYP enzymes in vitro and is not known to meaningfully affect mirtazapine exposure. No clinically significant interaction has been established.
How serious is the interaction between Anastrozole and Mirtazapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action needed beyond routine monitoring of mirtazapine tolerability.
What other medicines interact with Mirtazapine?
MediHelp also lists interactions of Mirtazapine with, for example, Isocarboxazid, Phenelzine, Pimozide. The full list is on the Mirtazapine page.
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