Drug interactions
Apomorphine + Triptorelin
Severity: Moderate
Apomorphine and Triptorelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Apomorphine can prolong the QT interval and is cautioned with other QT-prolonging drugs, and triptorelin may add to this through androgen deprivation. The combination may raise the risk of torsades de pointes.
What this interaction means in plain words
Apomorphine and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Apomorphine belongs to Central Nervous System; Triptorelin belongs to Endocrine.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Obtain baseline ECG and correct electrolyte abnormalities. Monitor for syncope or palpitations and consider ECG follow-up after starting.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triptorelin
Other interactions of Apomorphine
- Alosetron + Apomorphine Contraindicated
- Apomorphine + Cisapride Contraindicated
- Apomorphine + Dolasetron Contraindicated
- Apomorphine + Granisetron Contraindicated
- Apomorphine + Netupitant-palonosetron Contraindicated
- Apomorphine + Ondansetron Contraindicated
Frequently asked questions
Can I take Apomorphine with Triptorelin?
MediHelp rates the interaction as moderate. Apomorphine and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Apomorphine can prolong the QT interval and is cautioned with other QT-prolonging drugs, and triptorelin may add to this through androgen deprivation. The combination may raise the risk of torsades de pointes.
How serious is the interaction between Apomorphine and Triptorelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain baseline ECG and correct electrolyte abnormalities. Monitor for syncope or palpitations and consider ECG follow-up after starting.
What other medicines interact with Triptorelin?
MediHelp also lists interactions of Triptorelin with, for example, Amisulpride, Arsenic trioxide, Bedaquiline. The full list is on the Triptorelin page.
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