Drug interactions
Aripiprazole + Solifenacin
Severity: Minor
Aripiprazole and Solifenacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aripiprazole has minimal anticholinergic activity, so any additive antimuscarinic effect is small. Neither drug is a strong QT prolonger at usual doses. No clinically important interaction is established.
What this interaction means in plain words
Aripiprazole and Solifenacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Solifenacin belongs to Genitourinary.
Why it happens
Possible small additive antimuscarinic and QT effects; no established pharmacokinetic interaction.
What to do
No routine action is required; monitor for anticholinergic symptoms if other antimuscarinic drugs are also used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Solifenacin
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Solifenacin?
MediHelp rates the interaction as minor. Aripiprazole and Solifenacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aripiprazole has minimal anticholinergic activity, so any additive antimuscarinic effect is small. Neither drug is a strong QT prolonger at usual doses. No clinically important interaction is established.
How serious is the interaction between Aripiprazole and Solifenacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is required; monitor for anticholinergic symptoms if other antimuscarinic drugs are also used.
What other medicines interact with Solifenacin?
MediHelp also lists interactions of Solifenacin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Solifenacin page.
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