Drug interactions
Armodafinil + Galantamine
Severity: Minor
Armodafinil and Galantamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil may slightly lower galantamine concentrations through weak CYP3A4 induction, since galantamine is partly metabolized by CYP3A4. Clinical significance is expected to be small.
What this interaction means in plain words
Armodafinil and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Galantamine belongs to Central Nervous System.
Why it happens
CYP3A4 induction increases the metabolism of galantamine.
What to do
Monitor cognitive response and titrate galantamine if benefit diminishes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Armodafinil
Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Frequently asked questions
Can I take Armodafinil with Galantamine?
MediHelp rates the interaction as minor. Armodafinil and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil may slightly lower galantamine concentrations through weak CYP3A4 induction, since galantamine is partly metabolized by CYP3A4. Clinical significance is expected to be small.
How serious is the interaction between Armodafinil and Galantamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor cognitive response and titrate galantamine if benefit diminishes.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
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