Drug interactions
Artemether / lumefantrine + Dutasteride
Severity: Minor
Artemether / lumefantrine and Dutasteride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Artemether has weak CYP3A4 induction potential and might slightly lower dutasteride exposure. Antimalarial courses are short, so any effect is likely negligible.
What this interaction means in plain words
Artemether / lumefantrine and Dutasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible CYP3A4 induction by artemether increasing dutasteride metabolism.
What to do
No dose adjustment is needed. No specific monitoring is required for a short antimalarial course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dutasteride
- Dutasteride + Levoketoconazole Moderate
- Dutasteride + Nefazodone Moderate
- Dutasteride + Rifampin Moderate
- Dutasteride + St john's wort Moderate
- Amobarbital + Dutasteride Minor
- Aprepitant + Dutasteride Minor
Frequently asked questions
Can I take Artemether / lumefantrine with Dutasteride?
MediHelp rates the interaction as minor. Artemether / lumefantrine and Dutasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Artemether has weak CYP3A4 induction potential and might slightly lower dutasteride exposure. Antimalarial courses are short, so any effect is likely negligible.
How serious is the interaction between Artemether / lumefantrine and Dutasteride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. No specific monitoring is required for a short antimalarial course.
What other medicines interact with Dutasteride?
MediHelp also lists interactions of Dutasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Dutasteride page.
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