Drug interactions
Asciminib + Haloperidol
Severity: Major
Asciminib and Haloperidol: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can prolong the QT interval, so combined use raises the risk of torsades de pointes and serious ventricular arrhythmia. The risk is greater with higher asciminib doses, electrolyte disturbances or cardiac disease.
What this interaction means in plain words
Asciminib and Haloperidol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Asciminib belongs to Oncology; Haloperidol belongs to Central Nervous System.
Why it happens
Additive QT interval prolongation.
What to do
Avoid with asciminib 200 mg twice daily. At lower doses, monitor ECG and correct potassium and magnesium.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Asciminib
- Asciminib + Clarithromycin Major
- Asciminib + Dihydroergotamine Major
- Asciminib + Ergotamine Major
- Asciminib + Methadone Major
- Asciminib + Moxifloxacin Major
- Asciminib + Atorvastatin Moderate
Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Frequently asked questions
Can I take Asciminib with Haloperidol?
MediHelp rates the interaction as major. Asciminib and Haloperidol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents can prolong the QT interval, so combined use raises the risk of torsades de pointes and serious ventricular arrhythmia. The risk is greater with higher asciminib doses, electrolyte disturbances or cardiac disease.
How serious is the interaction between Asciminib and Haloperidol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid with asciminib 200 mg twice daily. At lower doses, monitor ECG and correct potassium and magnesium.
What other medicines interact with Asciminib?
MediHelp also lists interactions of Asciminib with, for example, Clarithromycin, Dihydroergotamine, Ergotamine. The full list is on the Asciminib page.
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