Drug interactions
Asciminib + Moxifloxacin
Severity: Major
Asciminib and Moxifloxacin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxifloxacin and asciminib can each prolong the QT interval, so together they raise the risk of torsades de pointes. Patients with electrolyte abnormalities or heart disease are at higher risk.
What this interaction means in plain words
Asciminib and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Asciminib belongs to Oncology; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Additive QT interval prolongation.
What to do
Avoid with asciminib 200 mg twice daily. At lower doses, use an alternative antibiotic if possible, otherwise monitor ECG and electrolytes.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Asciminib and Moxifloxacin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Asciminib
- Asciminib + Clarithromycin Major
- Asciminib + Dihydroergotamine Major
- Asciminib + Ergotamine Major
- Asciminib + Haloperidol Major
- Asciminib + Methadone Major
- Asciminib + Atorvastatin Moderate
Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Asciminib with Moxifloxacin?
MediHelp rates the interaction as major. Asciminib and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Moxifloxacin and asciminib can each prolong the QT interval, so together they raise the risk of torsades de pointes. Patients with electrolyte abnormalities or heart disease are at higher risk.
How serious is the interaction between Asciminib and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid with asciminib 200 mg twice daily. At lower doses, use an alternative antibiotic if possible, otherwise monitor ECG and electrolytes.
What other medicines interact with Asciminib?
MediHelp also lists interactions of Asciminib with, for example, Clarithromycin, Dihydroergotamine, Ergotamine. The full list is on the Asciminib page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
