Drug interactions
Atenolol-chlorthalidone + Cefpirome
Severity: Minor
Atenolol-chlorthalidone and Cefpirome: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefpirome and chlorthalidone are both cleared partly by the kidney, so competition for tubular secretion is theoretically possible. Clinical significance is expected to be negligible.
What this interaction means in plain words
Atenolol-chlorthalidone and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atenolol-chlorthalidone belongs to Cardiovascular; Cefpirome belongs to Anti Bacterial.
Why it happens
Theoretical competition for renal tubular secretion by organic anion transporters.
What to do
No specific action is required; check renal function in patients with renal impairment who receive both.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atenolol-chlorthalidone
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Atenolol-chlorthalidone with Cefpirome?
MediHelp rates the interaction as minor. Atenolol-chlorthalidone and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefpirome and chlorthalidone are both cleared partly by the kidney, so competition for tubular secretion is theoretically possible. Clinical significance is expected to be negligible.
How serious is the interaction between Atenolol-chlorthalidone and Cefpirome?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required; check renal function in patients with renal impairment who receive both.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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