Drug reference
cefpirome
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Cephalosporins)
Mechanism of action
Fourth-generation cephalosporin; has gram-negative coverage comparable to ceftazidime but better gram-positive coverage (comparable to ceftriaxone); is zwitterion and rapidly penetrates gram-negative cells; is best beta-lactam for IM administration; has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis
Common side effects
- Rash
- Positive Coombs test result without hemolysis
- Elevated alanine aminotransferase
- Hypophosphatemia
Related conditions
Frequently asked questions
What drug class is cefpirome?
cefpirome belongs to: Anti Bacterial.
How does cefpirome work?
Fourth-generation cephalosporin; has gram-negative coverage comparable to ceftazidime but better gram-positive coverage (comparable to ceftriaxone); is zwitterion and rapidly penetrates gram-negative cells; is best beta-lactam for IM administration; has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis
What are the common side effects of cefpirome?
Rash, Positive Coombs test result without hemolysis, Elevated alanine aminotransferase, Hypophosphatemia
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