Drug interactions
Atenolol-chlorthalidone + Verteporfin
Severity: Minor
Atenolol-chlorthalidone and Verteporfin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics are photosensitizing, so combining chlorthalidone with verteporfin may increase the risk of skin phototoxicity after photodynamic therapy. The effect is mostly theoretical and is relevant during the period of required light avoidance.
What this interaction means in plain words
Atenolol-chlorthalidone and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atenolol-chlorthalidone belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects of two agents.
What to do
Advise strict avoidance of direct sunlight and bright indoor light for the period specified in verteporfin labeling and use sun protection.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atenolol-chlorthalidone
Other interactions of Verteporfin
- Doxycycline + Verteporfin Moderate
- Griseofulvin + Verteporfin Moderate
- Minocycline + Verteporfin Moderate
- Tetracycline + Verteporfin Moderate
- Adapalene + Verteporfin Minor
- Amlodipine-hydrochlorothiazide-valsartan + Verteporfin Minor
Frequently asked questions
Can I take Atenolol-chlorthalidone with Verteporfin?
MediHelp rates the interaction as minor. Atenolol-chlorthalidone and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide diuretics are photosensitizing, so combining chlorthalidone with verteporfin may increase the risk of skin phototoxicity after photodynamic therapy. The effect is mostly theoretical and is relevant during the period of required light avoidance.
How serious is the interaction between Atenolol-chlorthalidone and Verteporfin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise strict avoidance of direct sunlight and bright indoor light for the period specified in verteporfin labeling and use sun protection.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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