Drug interactions
Tetracycline + Verteporfin
Severity: Moderate
Tetracycline and Verteporfin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetracyclines are photosensitizing, and verteporfin is a photosensitizing agent activated by light. Using both may increase the risk of skin phototoxicity such as sunburn-like reactions.
What this interaction means in plain words
Tetracycline and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Tetracycline belongs to Anti Bacterial; Verteporfin belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects of the two drugs.
What to do
Advise strict sun and bright-light protection during and after verteporfin therapy while on tetracycline. Consider whether tetracycline can be deferred or substituted.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tetracycline
- Acitretin + Tetracycline Contraindicated
- Methoxyflurane + Tetracycline Contraindicated
- Isotretinoin + Tetracycline Major
- Palovarotene + Tetracycline Major
- Strontium ranelate + Tetracycline Major
- Tetracycline + Tretinoin Major
Other interactions of Verteporfin
Frequently asked questions
Can I take Tetracycline with Verteporfin?
MediHelp rates the interaction as moderate. Tetracycline and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tetracyclines are photosensitizing, and verteporfin is a photosensitizing agent activated by light. Using both may increase the risk of skin phototoxicity such as sunburn-like reactions.
How serious is the interaction between Tetracycline and Verteporfin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise strict sun and bright-light protection during and after verteporfin therapy while on tetracycline. Consider whether tetracycline can be deferred or substituted.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
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