Drug interactions
Minocycline + Verteporfin
Severity: Moderate
Minocycline and Verteporfin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both minocycline and verteporfin can cause photosensitivity, so combined use may increase the risk of skin phototoxic reactions after verteporfin photodynamic therapy. The risk is mainly relevant in the days after the infusion.
What this interaction means in plain words
Minocycline and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Minocycline belongs to Anti Bacterial; Verteporfin belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects of two agents that can cause phototoxicity.
What to do
Advise strict avoidance of direct sunlight and bright indoor light on exposed skin and eyes for the period recommended after verteporfin. Consider deferring minocycline when feasible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Minocycline
- Acitretin + Minocycline Contraindicated
- Isotretinoin + Minocycline Contraindicated
- Cholera vaccine + Minocycline Major
- Methoxyflurane + Minocycline Major
- Minocycline + Palovarotene Major
- Minocycline + Pexidartinib Major
Other interactions of Verteporfin
Frequently asked questions
Can I take Minocycline with Verteporfin?
MediHelp rates the interaction as moderate. Minocycline and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both minocycline and verteporfin can cause photosensitivity, so combined use may increase the risk of skin phototoxic reactions after verteporfin photodynamic therapy. The risk is mainly relevant in the days after the infusion.
How serious is the interaction between Minocycline and Verteporfin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise strict avoidance of direct sunlight and bright indoor light on exposed skin and eyes for the period recommended after verteporfin. Consider deferring minocycline when feasible.
What other medicines interact with Minocycline?
MediHelp also lists interactions of Minocycline with, for example, Acitretin, Isotretinoin, Cholera vaccine. The full list is on the Minocycline page.
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