Drug interactions
Doxycycline + Verteporfin
Severity: Moderate
Doxycycline and Verteporfin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Doxycycline is a photosensitizing drug, and verteporfin is a photodynamic therapy agent that also causes photosensitivity. Combined use may increase the risk of skin phototoxicity after light exposure.
What this interaction means in plain words
Doxycycline and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxycycline belongs to Anti Bacterial; Verteporfin belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects of two phototoxic agents.
What to do
Counsel patients to avoid direct sunlight and bright indoor light and to use protective clothing for the period specified in verteporfin labeling.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Doxycycline
- Acitretin + Doxycycline Contraindicated
- Aminolevulinic acid + Doxycycline Major
- Cholera vaccine + Doxycycline Major
- Doxycycline + Isotretinoin Major
- Doxycycline + Methoxyflurane Major
- Doxycycline + Microbiota Major
Other interactions of Verteporfin
Frequently asked questions
Can I take Doxycycline with Verteporfin?
MediHelp rates the interaction as moderate. Doxycycline and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Doxycycline is a photosensitizing drug, and verteporfin is a photodynamic therapy agent that also causes photosensitivity. Combined use may increase the risk of skin phototoxicity after light exposure.
How serious is the interaction between Doxycycline and Verteporfin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid direct sunlight and bright indoor light and to use protective clothing for the period specified in verteporfin labeling.
What other medicines interact with Doxycycline?
MediHelp also lists interactions of Doxycycline with, for example, Acitretin, Aminolevulinic acid, Cholera vaccine. The full list is on the Doxycycline page.
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