Drug interactions
Amlodipine-hydrochlorothiazide-valsartan + Verteporfin
Severity: Minor
Amlodipine-hydrochlorothiazide-valsartan and Verteporfin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide is photosensitizing and may increase skin photosensitivity reactions after verteporfin therapy. The amlodipine effect is not established.
What this interaction means in plain words
Amlodipine-hydrochlorothiazide-valsartan and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.
Why it happens
Additive photosensitization from thiazide and photodynamic agent.
What to do
Counsel patients to avoid direct sunlight and bright light on skin for the period specified in verteporfin labeling.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Amlodipine-hydrochlorothiazide-valsartan and Verteporfin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Amlodipine-hydrochlorothiazide-valsartan
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Contraindicated
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide Contraindicated
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan Contraindicated
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan Major
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan Major
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan Major
Other interactions of Verteporfin
- Doxycycline + Verteporfin Moderate
- Griseofulvin + Verteporfin Moderate
- Minocycline + Verteporfin Moderate
- Tetracycline + Verteporfin Moderate
- Adapalene + Verteporfin Minor
- Amlodipine-olmesartan-hydrochlorothiazide + Verteporfin Minor
Frequently asked questions
Can I take Amlodipine-hydrochlorothiazide-valsartan with Verteporfin?
MediHelp rates the interaction as minor. Amlodipine-hydrochlorothiazide-valsartan and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide is photosensitizing and may increase skin photosensitivity reactions after verteporfin therapy. The amlodipine effect is not established.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Verteporfin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid direct sunlight and bright light on skin for the period specified in verteporfin labeling.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
