Drug interactions
Atenolol-chlorthalidone + Vildagliptin
Severity: Minor
Atenolol-chlorthalidone and Vildagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chlorthalidone can raise blood glucose and may partly offset the glucose-lowering effect of vildagliptin. Atenolol may blunt some symptoms of hypoglycemia, although vildagliptin alone rarely causes it.
What this interaction means in plain words
Atenolol-chlorthalidone and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atenolol-chlorthalidone belongs to Cardiovascular; Vildagliptin belongs to Endocrine.
Why it happens
Thiazide-related impaired glucose tolerance opposes the antidiabetic effect through pharmacodynamic antagonism.
What to do
Monitor glucose control after starting or adjusting the diuretic and intensify diabetes therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Atenolol-chlorthalidone and Vildagliptin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Atenolol-chlorthalidone
Other interactions of Vildagliptin
- Ciprofloxacin + Vildagliptin Moderate
- Deflazacort + Vildagliptin Moderate
- Dexamethasone + Vildagliptin Moderate
- Gemifloxacin + Vildagliptin Moderate
- Glimepiride + Vildagliptin Moderate
- Hydrochlorothiazide-lisinopril + Vildagliptin Moderate
Frequently asked questions
Can I take Atenolol-chlorthalidone with Vildagliptin?
MediHelp rates the interaction as minor. Atenolol-chlorthalidone and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chlorthalidone can raise blood glucose and may partly offset the glucose-lowering effect of vildagliptin. Atenolol may blunt some symptoms of hypoglycemia, although vildagliptin alone rarely causes it.
How serious is the interaction between Atenolol-chlorthalidone and Vildagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose control after starting or adjusting the diuretic and intensify diabetes therapy if control worsens.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
