Drug interactions
Atogepant + Dexlansoprazole
Severity: Minor
Atogepant and Dexlansoprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexlansoprazole is not a clinically meaningful CYP3A4 inhibitor, so a significant rise in atogepant exposure is not expected. Any interaction is likely theoretical.
What this interaction means in plain words
Atogepant and Dexlansoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atogepant belongs to Central Nervous System; Dexlansoprazole belongs to Gastrointestinal Tract.
Why it happens
Weak, probably clinically insignificant CYP3A4 inhibition by dexlansoprazole could slightly reduce atogepant clearance.
What to do
No dose adjustment is needed. Monitor routinely for atogepant adverse effects such as nausea and constipation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexlansoprazole
- Dexlansoprazole + Mavacamten Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Dexlansoprazole Major
- Atazanavir + Dexlansoprazole Major
- Dacomitinib + Dexlansoprazole Major
- Dasatinib + Dexlansoprazole Major
Other interactions of Atogepant
- Amobarbital + Atogepant Moderate
- Apalutamide + Atogepant Moderate
- Aprepitant + Atogepant Moderate
- Armodafinil + Atogepant Moderate
- Atogepant + Bosentan Moderate
- Atogepant + Carbamazepine Moderate
Frequently asked questions
Can I take Atogepant with Dexlansoprazole?
MediHelp rates the interaction as minor. Atogepant and Dexlansoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dexlansoprazole is not a clinically meaningful CYP3A4 inhibitor, so a significant rise in atogepant exposure is not expected. Any interaction is likely theoretical.
How serious is the interaction between Atogepant and Dexlansoprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Monitor routinely for atogepant adverse effects such as nausea and constipation.
What other medicines interact with Dexlansoprazole?
MediHelp also lists interactions of Dexlansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Dexlansoprazole page.
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