Drug interactions
Atogepant + Prednisone
Severity: Minor
Atogepant and Prednisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Prednisone is a weak CYP3A4 inducer at most, and atogepant is a CYP3A4 substrate, so a small reduction in atogepant exposure is theoretically possible. A clinically meaningful effect is not established.
What this interaction means in plain words
Atogepant and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atogepant belongs to Central Nervous System; Prednisone belongs to Endocrine.
Why it happens
Possible weak CYP3A4 induction by corticosteroid; not well established clinically.
What to do
No dose adjustment is usually needed. Monitor migraine control if prednisone is given long term at high doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Atogepant
- Amobarbital + Atogepant Moderate
- Apalutamide + Atogepant Moderate
- Aprepitant + Atogepant Moderate
- Armodafinil + Atogepant Moderate
- Atogepant + Bosentan Moderate
- Atogepant + Carbamazepine Moderate
Frequently asked questions
Can I take Atogepant with Prednisone?
MediHelp rates the interaction as minor. Atogepant and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Prednisone is a weak CYP3A4 inducer at most, and atogepant is a CYP3A4 substrate, so a small reduction in atogepant exposure is theoretically possible. A clinically meaningful effect is not established.
How serious is the interaction between Atogepant and Prednisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed. Monitor migraine control if prednisone is given long term at high doses.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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