Drug interactions
Atracurium + Lincomycin
Severity: Major
Atracurium and Lincomycin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lincomycin has neuromuscular blocking properties and can enhance nondepolarising blockade. Prolonged paralysis and respiratory depression may occur.
What this interaction means in plain words
Atracurium and Lincomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Atracurium belongs to Musculoskeletal; Lincomycin belongs to Anti Bacterial.
Why it happens
Lincosamide additive pre- and postsynaptic neuromuscular blockade.
What to do
Monitor neuromuscular function with train-of-four and titrate atracurium. Keep ventilatory support available until full recovery.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Atracurium
Other interactions of Lincomycin
- Cisatracurium + Lincomycin Major
- Lincomycin + Pancuronium Major
- Lincomycin + Rapacuronium Major
- Lincomycin + Rocuronium Major
- Lincomycin + Vecuronium Major
- Cholera vaccine + Lincomycin Moderate
Frequently asked questions
Can I take Atracurium with Lincomycin?
MediHelp rates the interaction as major. Atracurium and Lincomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lincomycin has neuromuscular blocking properties and can enhance nondepolarising blockade. Prolonged paralysis and respiratory depression may occur.
How serious is the interaction between Atracurium and Lincomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with train-of-four and titrate atracurium. Keep ventilatory support available until full recovery.
What other medicines interact with Atracurium?
MediHelp also lists interactions of Atracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Atracurium page.
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