Drug interactions
Atropine + Indacaterol-glycopyrronium
Severity: Moderate
Atropine and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are antimuscarinic, so combined use adds to systemic anticholinergic effects such as dry mouth, tachycardia, urinary retention, blurred vision and constipation. Patients with glaucoma or prostatic hyperplasia are at greater risk.
What this interaction means in plain words
Atropine and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Monitor for anticholinergic adverse effects, especially in elderly patients or those with glaucoma or urinary retention, and avoid prolonged duplicate therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Atropine
- Atropine + Eluxadoline Major
- Atropine + Henbane Major
- Atropine + Pramlintide Major
- Abobotulinumtoxina + Atropine Moderate
- Aclidinium + Atropine Moderate
- Amantadine + Atropine Moderate
Frequently asked questions
Can I take Atropine with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Atropine and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are antimuscarinic, so combined use adds to systemic anticholinergic effects such as dry mouth, tachycardia, urinary retention, blurred vision and constipation. Patients with glaucoma or prostatic hyperplasia are at greater risk.
How serious is the interaction between Atropine and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects, especially in elderly patients or those with glaucoma or urinary retention, and avoid prolonged duplicate therapy.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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