Drug interactions
Attapulgite + Metoclopramide
Severity: Minor
Attapulgite and Metoclopramide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Attapulgite is an adsorbent antidiarrheal that may bind co-administered drugs in the gut and slow transit. This could lower absorption of metoclopramide and weaken its effect.
What this interaction means in plain words
Attapulgite and Metoclopramide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible adsorption of metoclopramide in the gut lumen and reduced GI motility decreasing absorption; not well characterized.
What to do
Separate doses by about 2 hours, giving metoclopramide first, and watch for reduced response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Attapulgite and Metoclopramide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Metoclopramide
Frequently asked questions
Can I take Attapulgite with Metoclopramide?
MediHelp rates the interaction as minor. Attapulgite and Metoclopramide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Attapulgite is an adsorbent antidiarrheal that may bind co-administered drugs in the gut and slow transit. This could lower absorption of metoclopramide and weaken its effect.
How serious is the interaction between Attapulgite and Metoclopramide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by about 2 hours, giving metoclopramide first, and watch for reduced response.
What other medicines interact with Metoclopramide?
MediHelp also lists interactions of Metoclopramide with, for example, Amantadine, Amoxapine, Antipsychotics (e.g., haloperidol). The full list is on the Metoclopramide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
