Drug interactions
Avanafil + Griseofulvin
Severity: Minor
Avanafil and Griseofulvin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin may induce CYP3A4 and lower avanafil concentrations. Reduced exposure may weaken the erectile response.
What this interaction means in plain words
Avanafil and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Avanafil belongs to Genitourinary; Griseofulvin belongs to Anti Fungals.
Why it happens
Induction of CYP3A4 by griseofulvin increases avanafil metabolism.
What to do
Monitor erectile response during griseofulvin therapy. Consider an alternative approach if efficacy is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Avanafil
- Amyl nitrite + Avanafil Contraindicated
- Atazanavir + Avanafil Contraindicated
- Avanafil + Clarithromycin Contraindicated
- Avanafil + Conivaptan Contraindicated
- Avanafil + Darunavir Contraindicated
- Avanafil + Fosamprenavir Contraindicated
Other interactions of Griseofulvin
Frequently asked questions
Can I take Avanafil with Griseofulvin?
MediHelp rates the interaction as minor. Avanafil and Griseofulvin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin may induce CYP3A4 and lower avanafil concentrations. Reduced exposure may weaken the erectile response.
How serious is the interaction between Avanafil and Griseofulvin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor erectile response during griseofulvin therapy. Consider an alternative approach if efficacy is lost.
What other medicines interact with Avanafil?
MediHelp also lists interactions of Avanafil with, for example, Amyl nitrite, Atazanavir, Clarithromycin. The full list is on the Avanafil page.
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