Drug interactions
Azilsartan-chlorthalidone + Esmolol
Severity: Minor
Azilsartan-chlorthalidone and Esmolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Esmolol adds to the blood-pressure-lowering effect and may cause hypotension or bradycardia. Beta-blockade can slightly raise potassium by impairing cellular uptake, which is of limited significance with chlorthalidone.
What this interaction means in plain words
Azilsartan-chlorthalidone and Esmolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azilsartan-chlorthalidone belongs to Cardiovascular; Esmolol belongs to Cardiovascular.
Why it happens
Additive hemodynamic effects of beta-1 blockade with vasodilation and diuresis.
What to do
Monitor blood pressure and heart rate during esmolol infusion. Adjust the infusion rate if hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azilsartan-chlorthalidone
Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Frequently asked questions
Can I take Azilsartan-chlorthalidone with Esmolol?
MediHelp rates the interaction as minor. Azilsartan-chlorthalidone and Esmolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Esmolol adds to the blood-pressure-lowering effect and may cause hypotension or bradycardia. Beta-blockade can slightly raise potassium by impairing cellular uptake, which is of limited significance with chlorthalidone.
How serious is the interaction between Azilsartan-chlorthalidone and Esmolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during esmolol infusion. Adjust the infusion rate if hypotension occurs.
What other medicines interact with Azilsartan-chlorthalidone?
MediHelp also lists interactions of Azilsartan-chlorthalidone with, for example, Aliskiren, Sparsentan, Aceclofenac. The full list is on the Azilsartan-chlorthalidone page.
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