Drug interactions
Baloxavir marboxil + Magnesium
Severity: Moderate
Baloxavir marboxil and Magnesium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Baloxavir may bind magnesium and other polyvalent cations in the gut, which can reduce absorption and antiviral exposure. Magnesium-containing antacids and supplements are the main concern.
What this interaction means in plain words
Baloxavir marboxil and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Baloxavir marboxil belongs to Anti Virals; Magnesium belongs to Gastrointestinal Tract.
Why it happens
Chelation with polyvalent cations in the GI tract reduces baloxavir absorption.
What to do
Avoid taking baloxavir with magnesium-containing antacids, laxatives or supplements. Separate them by at least 2 hours where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Baloxavir marboxil and Magnesium, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Magnesium
- Ciprofloxacin + Magnesium Major
- Magnesium + Pancuronium Major
- Magnesium + Rocuronium Major
- Magnesium + Vecuronium Major
- Amikacin + Magnesium Moderate
- Amphotericin b deoxycholate + Magnesium Moderate
Other interactions of Baloxavir marboxil
- Aluminum hydroxide + Baloxavir marboxil Moderate
- Baloxavir marboxil + Calcium Moderate
- Baloxavir marboxil + Calcium carbonate Moderate
- Baloxavir marboxil + Carbonyl iron Moderate
- Baloxavir marboxil + Ferrous fumarate Moderate
- Baloxavir marboxil + Ferrous gluconate Moderate
Frequently asked questions
Can I take Baloxavir marboxil with Magnesium?
MediHelp rates the interaction as moderate. Baloxavir marboxil and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Baloxavir may bind magnesium and other polyvalent cations in the gut, which can reduce absorption and antiviral exposure. Magnesium-containing antacids and supplements are the main concern.
How serious is the interaction between Baloxavir marboxil and Magnesium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking baloxavir with magnesium-containing antacids, laxatives or supplements. Separate them by at least 2 hours where possible.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
