Drug interactions
Balsalazide + Piroxicam
Severity: Minor
Balsalazide and Piroxicam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Piroxicam is an acidic NSAID that could compete with balsalazide metabolites for renal tubular secretion. The effect is likely small. NSAIDs may also worsen inflammatory bowel disease and renal function.
What this interaction means in plain words
Balsalazide and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Balsalazide belongs to Gastrointestinal Tract; Piroxicam belongs to Musculoskeletal.
Why it happens
Possible competition for renal tubular anionic secretion; this is largely theoretical.
What to do
No dose adjustment is needed; monitor renal function and bowel symptoms during extended co-therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Balsalazide
Other interactions of Piroxicam
- Ketorolac intranasal + Piroxicam Contraindicated
- Ketorolac + Piroxicam Contraindicated
- Aceclofenac + Piroxicam Major
- Acemetacin + Piroxicam Major
- Acetylsalicylic acid + Piroxicam Major
- Alteplase + Piroxicam Major
Frequently asked questions
Can I take Balsalazide with Piroxicam?
MediHelp rates the interaction as minor. Balsalazide and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Piroxicam is an acidic NSAID that could compete with balsalazide metabolites for renal tubular secretion. The effect is likely small. NSAIDs may also worsen inflammatory bowel disease and renal function.
How serious is the interaction between Balsalazide and Piroxicam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor renal function and bowel symptoms during extended co-therapy.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
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