Drug interactions
Basiliximab + Everolimus
Severity: Moderate
Basiliximab and Everolimus: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Everolimus and basiliximab both suppress immune responses and together increase susceptibility to infection. This combination is used in transplant protocols, where it requires careful oversight.
What this interaction means in plain words
Basiliximab and Everolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Basiliximab belongs to Miscellaneous; Everolimus belongs to Oncology.
Why it happens
Additive immunosuppression via mTOR inhibition and IL-2 receptor blockade of T cells.
What to do
Use only within a defined transplant immunosuppression protocol and monitor for infection. Consider prophylaxis against opportunistic infections as per protocol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Basiliximab with Everolimus?
MediHelp rates the interaction as moderate. Basiliximab and Everolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Everolimus and basiliximab both suppress immune responses and together increase susceptibility to infection. This combination is used in transplant protocols, where it requires careful oversight.
How serious is the interaction between Basiliximab and Everolimus?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only within a defined transplant immunosuppression protocol and monitor for infection. Consider prophylaxis against opportunistic infections as per protocol.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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