Drug interactions
Basiliximab + Ozanimod
Severity: Moderate
Basiliximab and Ozanimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ozanimod lowers circulating lymphocyte counts and basiliximab blocks T-cell activation, so together they may increase the risk of infection. The effect of ozanimod can persist for some time after stopping.
What this interaction means in plain words
Basiliximab and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Basiliximab belongs to Miscellaneous; Ozanimod belongs to Central Nervous System.
Why it happens
Additive immunosuppression from S1P receptor modulation with lymphocyte sequestration and IL-2 receptor blockade.
What to do
Monitor for infection and check lymphocyte counts. Take into account the lingering effects of ozanimod when starting immunosuppressive therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Basiliximab with Ozanimod?
MediHelp rates the interaction as moderate. Basiliximab and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ozanimod lowers circulating lymphocyte counts and basiliximab blocks T-cell activation, so together they may increase the risk of infection. The effect of ozanimod can persist for some time after stopping.
How serious is the interaction between Basiliximab and Ozanimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for infection and check lymphocyte counts. Take into account the lingering effects of ozanimod when starting immunosuppressive therapy.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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