Drug interactions
Bazedoxifene-conjugated estrogens + Cefotetan
Severity: Minor
Bazedoxifene-conjugated estrogens and Cefotetan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Broad-spectrum antibiotics might reduce estrogen reabsorption by changing intestinal flora. Any effect on menopausal hormone therapy is likely small and unproven.
What this interaction means in plain words
Bazedoxifene-conjugated estrogens and Cefotetan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bazedoxifene-conjugated estrogens belongs to Endocrine; Cefotetan belongs to Anti Bacterial.
Why it happens
Theoretical decrease in enterohepatic recirculation of estrogens from altered gut flora.
What to do
No dose change is needed. Reassess if menopausal symptoms recur during treatment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bazedoxifene-conjugated estrogens
- Anastrozole + Bazedoxifene-conjugated estrogens Contraindicated
- Bazedoxifene-conjugated estrogens + Ospemifene Contraindicated
- Antithrombin alfa + Bazedoxifene-conjugated estrogens Major
- Antithrombin iii + Bazedoxifene-conjugated estrogens Major
- Bazedoxifene-conjugated estrogens + Bemiparin Major
- Bazedoxifene-conjugated estrogens + Carbamazepine Major
Other interactions of Cefotetan
- Cefotetan + Dronabinol Contraindicated
- Cefotetan + Warfarin Major
- Amikacin + Cefotetan Moderate
- Argatroban + Cefotetan Moderate
- Cefotetan + Dalteparin Moderate
- Cefotetan + Enoxaparin Moderate
Frequently asked questions
Can I take Bazedoxifene-conjugated estrogens with Cefotetan?
MediHelp rates the interaction as minor. Bazedoxifene-conjugated estrogens and Cefotetan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Broad-spectrum antibiotics might reduce estrogen reabsorption by changing intestinal flora. Any effect on menopausal hormone therapy is likely small and unproven.
How serious is the interaction between Bazedoxifene-conjugated estrogens and Cefotetan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Reassess if menopausal symptoms recur during treatment.
What other medicines interact with Bazedoxifene-conjugated estrogens?
MediHelp also lists interactions of Bazedoxifene-conjugated estrogens with, for example, Anastrozole, Ospemifene, Antithrombin alfa. The full list is on the Bazedoxifene-conjugated estrogens page.
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