Drug interactions
Beclomethasone inhaled + Leflunomide
Severity: Minor
Beclomethasone inhaled and Leflunomide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled beclomethasone has low systemic exposure at usual doses, so any added immunosuppression or marrow toxicity with leflunomide is likely small. The labeling concern about combining leflunomide with other immunosuppressants applies mainly to systemic agents.
What this interaction means in plain words
Beclomethasone inhaled and Leflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible minor additive immunosuppression, limited by low systemic absorption of the inhaled steroid.
What to do
No change is usually needed; continue routine blood count and liver monitoring for leflunomide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Leflunomide
- Bcg vaccine live + Leflunomide Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Leflunomide Contraindicated
- Leflunomide + Measles mumps and rubella vaccine live Contraindicated
- Leflunomide + Measles mumps rubella and varicella vaccine live Contraindicated
- Leflunomide + Measles vaccine Contraindicated
- Leflunomide + Smallpox vaccine live Contraindicated
Frequently asked questions
Can I take Beclomethasone inhaled with Leflunomide?
MediHelp rates the interaction as minor. Beclomethasone inhaled and Leflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled beclomethasone has low systemic exposure at usual doses, so any added immunosuppression or marrow toxicity with leflunomide is likely small. The labeling concern about combining leflunomide with other immunosuppressants applies mainly to systemic agents.
How serious is the interaction between Beclomethasone inhaled and Leflunomide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is usually needed; continue routine blood count and liver monitoring for leflunomide.
What other medicines interact with Leflunomide?
MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Leflunomide page.
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