Drug interactions
Bedaquiline + Formoterol-mometasone
Severity: Moderate
Bedaquiline and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bedaquiline prolongs the QT interval, and formoterol may add a small additional effect and lower potassium. The combination raises arrhythmia risk, particularly in patients with other risk factors.
What this interaction means in plain words
Bedaquiline and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bedaquiline belongs to Anti Bacterial; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta2-agonist hypokalaemia increasing susceptibility.
What to do
Perform ECG monitoring and correct potassium, magnesium and calcium abnormalities. Use the lowest effective formoterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Bedaquiline
- Bedaquiline + Ziprasidone Contraindicated
- Alfuzosin + Bedaquiline Major
- Amiodarone + Bedaquiline Major
- Amisulpride + Bedaquiline Major
- Amitriptyline + Bedaquiline Major
- Amobarbital + Bedaquiline Major
Frequently asked questions
Can I take Bedaquiline with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Bedaquiline and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bedaquiline prolongs the QT interval, and formoterol may add a small additional effect and lower potassium. The combination raises arrhythmia risk, particularly in patients with other risk factors.
How serious is the interaction between Bedaquiline and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform ECG monitoring and correct potassium, magnesium and calcium abnormalities. Use the lowest effective formoterol dose.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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