Drug interactions
Benazepril + Methylphenidate
Severity: Minor
Benazepril and Methylphenidate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Methylphenidate can raise blood pressure and heart rate and may reduce the effectiveness of antihypertensives such as benazepril. The effect is usually modest.
What this interaction means in plain words
Benazepril and Methylphenidate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benazepril belongs to Cardiovascular; Methylphenidate belongs to Central Nervous System.
Why it happens
Pharmacodynamic antagonism through sympathomimetic pressor effects.
What to do
Check blood pressure at baseline and periodically after methylphenidate is started or increased. Adjust antihypertensive dosing if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Other interactions of Methylphenidate
- Isocarboxazid + Methylphenidate Contraindicated
- Linezolid + Methylphenidate Contraindicated
- Methylphenidate + Phenelzine Contraindicated
- Methylphenidate + Procarbazine Contraindicated
- Methylphenidate + Rasagiline Contraindicated
- Methylphenidate + Safinamide Contraindicated
Frequently asked questions
Can I take Benazepril with Methylphenidate?
MediHelp rates the interaction as minor. Benazepril and Methylphenidate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Methylphenidate can raise blood pressure and heart rate and may reduce the effectiveness of antihypertensives such as benazepril. The effect is usually modest.
How serious is the interaction between Benazepril and Methylphenidate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood pressure at baseline and periodically after methylphenidate is started or increased. Adjust antihypertensive dosing if control worsens.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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