Drug interactions
Benazepril + Mirabegron
Severity: Minor
Benazepril and Mirabegron: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mirabegron can raise blood pressure in some patients, which could partly offset the effect of an ACE inhibitor such as benazepril. The effect is generally small and not well documented as a significant interaction.
What this interaction means in plain words
Benazepril and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benazepril belongs to Cardiovascular; Mirabegron belongs to Genitourinary.
Why it happens
Opposing pharmacodynamic effects on blood pressure; mirabegron may cause modest pressure increases.
What to do
Monitor blood pressure after mirabegron is started and adjust antihypertensive therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mirabegron
- Digoxin + Mirabegron Major
- Flecainide + Mirabegron Major
- Mirabegron + Propafenone Major
- Mirabegron + Thioridazine Major
- Amitriptyline + Mirabegron Moderate
- Amoxapine + Mirabegron Moderate
Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Frequently asked questions
Can I take Benazepril with Mirabegron?
MediHelp rates the interaction as minor. Benazepril and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mirabegron can raise blood pressure in some patients, which could partly offset the effect of an ACE inhibitor such as benazepril. The effect is generally small and not well documented as a significant interaction.
How serious is the interaction between Benazepril and Mirabegron?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure after mirabegron is started and adjust antihypertensive therapy if control worsens.
What other medicines interact with Mirabegron?
MediHelp also lists interactions of Mirabegron with, for example, Digoxin, Flecainide, Propafenone. The full list is on the Mirabegron page.
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