Drug interactions
Benazepril + Potassium iodide
Severity: Moderate
Benazepril and Potassium iodide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide contains potassium that can add to the potassium retention caused by benazepril. Hyperkalemia is possible, especially with prolonged use or reduced kidney function.
What this interaction means in plain words
Benazepril and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Potassium iodide belongs to Endocrine.
Why it happens
ACE inhibitor-induced aldosterone suppression reduces potassium excretion, adding to the potassium delivered by the iodide salt.
What to do
For short courses the risk is small, but monitor serum potassium if potassium iodide is used repeatedly or in patients with renal impairment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Benazepril with Potassium iodide?
MediHelp rates the interaction as moderate. Benazepril and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Potassium iodide contains potassium that can add to the potassium retention caused by benazepril. Hyperkalemia is possible, especially with prolonged use or reduced kidney function.
How serious is the interaction between Benazepril and Potassium iodide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: For short courses the risk is small, but monitor serum potassium if potassium iodide is used repeatedly or in patients with renal impairment.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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