Drug interactions
Bendamustine + Elagolix
Severity: Minor
Bendamustine and Elagolix: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak P-gp inhibitor and may modestly raise concentrations of P-gp substrates. The effect on bendamustine is likely small.
What this interaction means in plain words
Bendamustine and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bendamustine belongs to Oncology; Elagolix belongs to Musculoskeletal.
Why it happens
P-gp inhibition may reduce bendamustine efflux.
What to do
No dose adjustment is needed; monitor blood counts as part of routine bendamustine care.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bendamustine
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Bendamustine with Elagolix?
MediHelp rates the interaction as minor. Bendamustine and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak P-gp inhibitor and may modestly raise concentrations of P-gp substrates. The effect on bendamustine is likely small.
How serious is the interaction between Bendamustine and Elagolix?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor blood counts as part of routine bendamustine care.
What other medicines interact with Bendamustine?
MediHelp also lists interactions of Bendamustine with, for example, Axicabtagene ciloleucel, Brexucabtagene autoleucel, Chlorambucil. The full list is on the Bendamustine page.
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