Drug interactions
Bendroflumethiazide + Magnesium sulphate
Severity: Minor
Bendroflumethiazide and Magnesium sulphate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics increase urinary magnesium loss and can cause hypomagnesemia with long-term use. This may lessen the effect of magnesium therapy and increase arrhythmia risk, especially with concurrent hypokalemia.
What this interaction means in plain words
Bendroflumethiazide and Magnesium sulphate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Thiazides increase renal magnesium excretion.
What to do
Monitor serum magnesium and potassium during long-term combined therapy, and replace as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium sulphate
- Amikacin + Magnesium sulphate Moderate
- Amphotericin b deoxycholate + Magnesium sulphate Moderate
- Atracurium + Magnesium sulphate Moderate
- Baloxavir marboxil + Magnesium sulphate Moderate
- Ciprofloxacin + Magnesium sulphate Moderate
- Cisatracurium + Magnesium sulphate Moderate
Frequently asked questions
Can I take Bendroflumethiazide with Magnesium sulphate?
MediHelp rates the interaction as minor. Bendroflumethiazide and Magnesium sulphate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide diuretics increase urinary magnesium loss and can cause hypomagnesemia with long-term use. This may lessen the effect of magnesium therapy and increase arrhythmia risk, especially with concurrent hypokalemia.
How serious is the interaction between Bendroflumethiazide and Magnesium sulphate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium and potassium during long-term combined therapy, and replace as needed.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
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