Drug interactions
Bicalutamide + Capivasertib
Severity: Minor
Bicalutamide and Capivasertib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bicalutamide weakly inhibits CYP3A4 and could slightly raise capivasertib exposure. This may increase hyperglycemia, diarrhea or rash, though the effect is likely small.
What this interaction means in plain words
Bicalutamide and Capivasertib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bicalutamide belongs to Endocrine; Capivasertib belongs to Oncology.
Why it happens
Bicalutamide weakly inhibits CYP3A4, reducing capivasertib metabolism.
What to do
Monitor blood glucose and for diarrhea or rash. Reduce the capivasertib dose if adverse effects become significant.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bicalutamide
- Bicalutamide + Lomitapide Major
- Aminolevulinic acid + Bicalutamide Moderate
- Bicalutamide + Eliglustat Moderate
- Bicalutamide + Flibanserin Moderate
- Bicalutamide + Ivosidenib Moderate
- Bicalutamide + Lonafarnib Moderate
Other interactions of Capivasertib
Frequently asked questions
Can I take Bicalutamide with Capivasertib?
MediHelp rates the interaction as minor. Bicalutamide and Capivasertib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bicalutamide weakly inhibits CYP3A4 and could slightly raise capivasertib exposure. This may increase hyperglycemia, diarrhea or rash, though the effect is likely small.
How serious is the interaction between Bicalutamide and Capivasertib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and for diarrhea or rash. Reduce the capivasertib dose if adverse effects become significant.
What other medicines interact with Bicalutamide?
MediHelp also lists interactions of Bicalutamide with, for example, Lomitapide, Aminolevulinic acid, Eliglustat. The full list is on the Bicalutamide page.
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