Drug interactions
Bicalutamide + Tamsulosin
Severity: Minor
Bicalutamide and Tamsulosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bicalutamide has shown only weak CYP3A4 inhibition in vitro, so a meaningful rise in tamsulosin levels is unlikely. Clinical significance is minimal.
What this interaction means in plain words
Bicalutamide and Tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bicalutamide belongs to Endocrine; Tamsulosin belongs to Genitourinary.
Why it happens
Weak, theoretical inhibition of CYP3A4 metabolism of tamsulosin.
What to do
No dose change is needed. Be aware of dizziness or hypotension if symptoms emerge.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tamsulosin
- Alfuzosin + Tamsulosin Major
- Avanafil + Tamsulosin Major
- Ceritinib + Tamsulosin Major
- Clarithromycin + Tamsulosin Major
- Cobicistat + Tamsulosin Major
- Doxazosin + Tamsulosin Major
Other interactions of Bicalutamide
- Bicalutamide + Lomitapide Major
- Aminolevulinic acid + Bicalutamide Moderate
- Bicalutamide + Eliglustat Moderate
- Bicalutamide + Flibanserin Moderate
- Bicalutamide + Ivosidenib Moderate
- Bicalutamide + Lonafarnib Moderate
Frequently asked questions
Can I take Bicalutamide with Tamsulosin?
MediHelp rates the interaction as minor. Bicalutamide and Tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bicalutamide has shown only weak CYP3A4 inhibition in vitro, so a meaningful rise in tamsulosin levels is unlikely. Clinical significance is minimal.
How serious is the interaction between Bicalutamide and Tamsulosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Be aware of dizziness or hypotension if symptoms emerge.
What other medicines interact with Tamsulosin?
MediHelp also lists interactions of Tamsulosin with, for example, Alfuzosin, Avanafil, Ceritinib. The full list is on the Tamsulosin page.
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